As the Industrial Internet of Things (IIoT) expands into ever more areas, issues with security become critical. Some of the greatest benefits to be gained come from connecting systems and sensors on the factory floor to corporate systems and multiple sites. The downside is that this leaves these systems, which are critical to the business, open to intrusions, potentially negating the benefits. There are two areas of vulnerability. The first is disruption of operations. The second is the theft of data. In this course, we will look at some of the issues involved and potential solutions to both problems. These include some standard solutions to protect infrastructure as well as solutions that can be embedded in the protocol stack of the devices themselves.