Many operations in modern industrial enterprises have multiple facilities, including warehousing and distribution sites. These will have many devices internally and will need to work together. This can be done by direct connection, or by integration with centralized computing resources, often including cloud computing and storage. The centralized systems will perform operations such as Manufacturing Resource Planning (MRP) and analytics. Data transmitted between plants and central facilities can present many challenges. In this lecture we will discuss how these are met and how to implement them.