Thanks, bobjengr, glad you like the story. This has just been announced in R&D, so I doubt if they've gotten any sort of medical approvals yet, or it would have been mentioned. More details about Tufts' work may be available on their website, or in the (unfortunately for-pay) research article we give a link to in the article. Let us know if you find out!
Great post Ann.To me, the most fascinating part is fact that the material is biodegradable.It does its job then goes away—absorbed into the human "system".Do you know how long Tuffs University worked on the project and whether or not necessary medical approvals have been awarded?I would love to know what length of time was needed to develop this marvelous application.Again, great post.
You're right, Ann, the emerging economies are young. But the mature economies have the medical needs, and the mature economies also have the development dollars. The againg population will create a growing need that will support medical developments.
Rob, I agree. I think there are a few factors driving developments like this, including an aging population (at least in the US, Japan and Europe, although the opposite trend is occurring in the ROW and it, in fact, trumps the aging trend in these three areas).
Thanks, Dave. I also noticed that the silk scaffold strength doesn't match up to the strength of bone, which was, after all, designed to do something silk was not. I often suspect that we may have to learn how to design new materials at the molecular level in order to make what we need out of non-original materials.
@Ann: Wow, another fascinating article. Not only did the Tufts research group use a biological material, but they also used a bio-inspired principle of combining large fibers with microfibers. It's also interesting that the fiber scaffolds that were most bone-like (i.e. the most rigid) were the most effective in promoting differentiation of stem cells into bone cells. In other words, not only are they strong, but they also help the body repair itself.
On the other hand, it's a little humbling that the best scaffold material still had a compressive strength that is nearly an order of magnitude less than that of bone (13 MPa vs. 100 MPa). Clearly, we have a long way to go before we can improve on what nature has, after all, taken billions of years to develop.
Nadine, there was no information about whether larvae are removed before the cocoons are boiled. It would be interesting to know if, when that is not done, that's for expediency or because it produces a better silk fiber.
Wal-Mart will hold its second Made in the USA Open Call July 7-8, at its headquarters in Bentonville, Ark. The event will be a repeat effort by the world’s biggest seller of consumer goods to increase the amount of US-made products it sells in Wal-Mart stores, in Sam’s Club members-only wholesale outlets, and on walmart.com.
From design feasibility, to development, to production, having the right information to make good decisions can ultimately keep a product from failing validation. The key is highly focused information that doesn’t come from conventional, statistics-based tests but from accelerated stress testing.
There’s a good chance that a few of the things mentioned here won't fully come to fruition in 2015 but rather much later down the line. However, as Malcolm X once said, "The future belongs to those who prepare for it today."
Focus on Fundamentals consists of 45-minute on-line classes that cover a host of technologies. You learn without leaving the comfort of your desk. All classes are taught by subject-matter experts and all are archived. So if you can't attend live, attend at your convenience.