Mark Rumreich built a puzzle for his nephew Nathan. After building a small version of the "Nathan," he decided to ratchet up the stakes with the MEGA-NATHAN. The puzzle has a grid of 4x4 toggle switches on the face of a box. A puzzle pattern is set inside the box using a matching 4x4 switch grid. The back cover is then closed to conceal the solution from Nathan. When the front switches are set to the correct pattern, an internal buzzer buzzes, and Nathan wins. Problem is, there are 65,536 (2^16) possible switch combinations. So Mark devised a series of hints that alert Nathan to the correct solution path.
Last year at Hannover Fair, lots of people were talking about Industry 4.0. This is a concept that seems to have a different name in every region. I’ve been referring to it as the Industrial Internet of Things (IIoT), not to be confused with the plain old Internet of Things (IoT). Others refer to it as the Connected Industry, the smart factory concept, M2M, data extraction, and so on.
Some of the biggest self-assembled building blocks and structures made from engineered DNA have been developed by researchers at Harvard's Wyss Institute. The largest, a hexagonal prism, is one-tenth the size of an average bacterium.
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