Terry Blumenthal is not a medical device designer, but he has an important message for engineers who design defibrillators. The Wake Forest University psychologist is working with cardiologist Charles Swerdlow to find ways of reducing the painful electric shock administered by defibrillators when they activate. "We considered using weaker electric shocks, but that didn't work," says Swerdlow. "Then we tried changing the shape of the waveform, but that has not yet been successful," he explains. They eventually found that when a painless electric "pre-pulse" precedes a painful electric shock, the pre-pulse seems to reduce the body's startle response and minimize pain. "The pre-pulse interrupts everything, including the subsequent processing of pain," says Blumenthal. "It diminishes the neural circuits' ability to respond to subsequent painful stimulus," he says. Testing the hypothesis involved delivering 150V shocks to volunteers, who then rated the shock's painfulness with and without pre-pulses. Although volunteers received the same shock, the painfulness was rated lower with the pre-pulse. "There may be a variety of ways to integrate these finding into other applications using sound, sight, and other modalities," says Blumenthal. For more information, e-mail firstname.lastname@example.org.
Producing high-quality end-production metal parts with additive manufacturing for applications like aerospace and medical requires very tightly controlled processes and materials. New standards and guidelines for machines and processes, materials, and printed parts are underway from bodies such as ASTM International.
Engineers at the University of San Diego’s Jacobs School of Engineering have designed biobatteries on commercial tattoo paper, with an anode and cathode screen-printed on and modified to harvest energy from lactate in a person’s sweat.
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