Researchers at the National Institute of Standards and Technology (www.nist.gov) have developed a new method to produce uniform, self-assembled nanocells for drug therapies, such as chemotherapy, in which dosage depends critically on the size of the nanocells. The new method uses micrometer-size channels etched into a device to produce self-assembled liposomes—a type of artificial nanocell—of specific sizes from 100 to 240 nm. A stream of lipids dissolved in alcohol is directed at an intersection of two channels while a water-based liquid containing medicines or other substances is sent toward the lipid stream from two opposing directions. Self-assembled nanocells are formed when the lipids surround the water rather than mixing with it.
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