naperlou, I think you're right. This is yet another case of using natural materials to solve problems by taking advantage of their inherent characteristics, instead of trying to force synthetic materials to do something they are not made to do, or can't easily do (be bio-compatible and biodegradable, in this instance). Of course, the researchers had to design silk matrices to mimic bone, but that apparently wasn't too tough to achieve.
This is an exciting development, Ann. The biomedical field is just going to get more and more interesting in coming years. If this material could help those with osteoporosis, it could have a major impact of the quality of life for millions.
williamlweaver, thanks for the enthusiastic response from someone who's worked with materials aimed at similar applications. The scenario you mention sounds very similar to the idea the Tufts researchers mention, of drug delivery over a short period, and then the scaffold biodegrading in situ.
gsmith, I doubt if this has been used on actual patients yet--this is an R&D project at a university, and the announcement would most likely have mentioned any beta testing. If we hear anything about actual testing, I'll be happy to report on it.
Wow, Ann! This is fantastic. I've worked with Poly(methyl methacrylate) (PMMA) bone cement along with researchers here at the Einstein Medical Center here in Philadelphia. Our research was investigating the mechanical properties (strength) of PMMA after having chemotherapeutic agents mixed in with the monomer before polymerization and the elution rates of the drugs after they were placed in vivo. The PMMA retained its strength for the most part, but the slow elution rates of most drugs meant a patient would have to endure low dose chemo drugs over many years to decades.
A biodegradable bone scaffold material such as this could be used to deliver the chemo drugs over a finite amount of time. Promising applications...
Dow Chemical and several other companies have launched a program in Omaha, Neb. to divert about 36 tons of plastics from landfills in its first phase, and convert it into energy used for cement production.
A make-your-own Star Wars Sith Lightsaber hilt is heftier and better-looking than most others out there, according to its maker, Sean Charlesworth. You can 3D print it from free source files, and there's even a hardware kit available -- not free -- so you can build one just in time for Halloween.
Some next-generation bio-based materials are superior in performance to their petro-based counterparts, but also face some commercial challenges. This is especially true of certain biopolymers, adhesives, coatings, and advanced materials.
Cars and other vehicles, as well as electronics and medical devices, continue to lead the use cases for the new plastics products we've been seeing, as engineers design products for tougher environments.
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