HOME  |  NEWS  |  BLOGS  |  MESSAGES  |  FEATURES  |  VIDEOS  |  WEBINARS  |  INDUSTRIES  |  FOCUS ON FUNDAMENTALS
  |  REGISTER  |  LOGIN  |  HELP
Blogs
Engineering Materials

Artificial Lung Is Microfluidics Marvel

NO RATINGS
1 saves
View Comments: Oldest First|Newest First|Threaded View
Page 1/2  >  >>
Alexander Wolfe
User Rank
Blogger
Biotech frontier
Alexander Wolfe   8/4/2011 7:58:26 AM
NO RATINGS
The intersection of biology and mechanical, electrical, computer and manufacturing engineering is really where the action is going to be in the 21st century. This story is a great example. I wonder, in your experience, Doug, do the medical professionals who are part of these teams have enough understanding of the non-biology stuff to be able to make as big a contribution as possible. I.e., if there was more cross-training, would some of these things evolve in faster or different ways? I realize that, in this case and in many others, the materials, cost, and miniaturization are the gating challenges. I'm just speculating as to the energizing effect of more cross-pollination within the collaborative teams. Great story.

Beth Stackpole
User Rank
Blogger
Re: Biotech frontier
Beth Stackpole   8/4/2011 8:12:43 AM
NO RATINGS
I have to agree with Alex on the potential for this intersection of technologies and disciplines and the impact it is having on medical advancements. Obviously, biomedical engineering is an important field, but I wonder what other new cross-discipline domains and training programs are emerging to better blend "the biology stuff with the non-biology stuff."

As someone who recently lost a family member (post transplant) to advanced lung disease, this story is particularly relevant. It's heartening to see how much process they're making, and that added detail about the first prototype being developed with additive manufacturing technologies points up another emerging area that has huge potential for emerging medical applications. Great story, Doug.

Douglas Smock
User Rank
Platinum
Re: Biotech frontier
Douglas Smock   8/4/2011 9:01:53 AM
NO RATINGS
There is usually great interdisciplinary involvement in these types of projects. Usually mechanical engineers are involved. And yes, these people really know their stuff. They are plumbing whole new depths of knowledge unknown in traditional corporate development projects. I have been really impressed with the level of understanding these groups have in areas of polymer science where corporations have largely given up --- polymers for implants. I touched on this recently in another post. Very specialized groups are operating under the radar to develop bioresorbable polymers for implants, for example. This project also shows the tremendous potential for additive manufacturing in microfluidics.

OhmsLaw
User Rank
Gold
Re: Biotech frontier
OhmsLaw   8/4/2011 10:14:19 AM
NO RATINGS
Any attempt to mimic human parts will be humbled by the truly amazing human ability for reliability, performance and size and certainly requires expertise in dozens of fields of science. 

Considering we can survive contstant attack of viruses and bacteria and other parasites. Also we don't often rust, or need a power flush, routine change of antifreeze or need CLR flush treatments and use nano-osmotic effects to exchange CO2 for O2 and aren't affected much by microwave and RF ringing thru our lungs and can cough sputum if needed.... and oh ya have an automatic or manual feature with a  lifetime warranty on the air pump in our bellies.

.... a man-made design has a tough job to mimic  a lung, in literaly hundreds of different chemical/physical properties.

Kudos.

 

Anthony   (aka Tony Stewart)

Douglas Smock
User Rank
Platinum
Re: Biotech frontier
Douglas Smock   8/4/2011 10:40:10 AM
NO RATINGS
I absolutely agree Ohms. The human body is a wonder that no engineer or scientist could ever begin to replicate in a meaningful way. The great advance I described at CWRU only lasts a few hours in the lab.  We are taking steps tinier than the tiniest baby steps. And even those accomplishments are inspiring.

jpotkay
User Rank
Iron
Re: Biotech frontier
jpotkay   8/4/2011 12:15:02 PM
NO RATINGS
Hi Alex. I am the lead researcher on the work and Doug asked me to log in and comment about our research team. Our cross-disciplinary team involves the following:

* One specialist in microfabrication and microfluidics (myself)

* One cardiothoracic surgeon and one pulmonary physician

* Two experts in bio- and blood- compatible coatings

* One expert in biomimetic artificial vasculature who also has some previous experience in artificial lung design.

As you can see, we have quite a wide array of backgrounds which are all needed to make this project a success. However, as part of this project, we are all experiencing some cross training which is making us better at what we do as well.

Please let me know if you have any other questions.

Thanks for your interest in the work.

-Joe

SalvadorRomo
User Rank
Iron
Excelent article
SalvadorRomo   8/4/2011 10:07:29 PM
NO RATINGS
Doug, excelent article, I wish if in addition to the interdicipline mentioned in another post, at some point there is an story about the equipment used for the CAD design and the Additive Manufacturing.

Again thanks for this great story,

Salvador

HaroldHallikainen
User Rank
Iron
Come a long way!
HaroldHallikainen   8/5/2011 11:40:34 AM
NO RATINGS
I'm very impressed with the progress made in this field! My father was involved in the manufacture of heart/lung machines in the 1960s. Info on machines of that time is available at:

http://www.hallikainen.org/hi/brochures/1235.pdf

http://www.hallikainen.org/hi/brochures/1273.pdf

http://www.hallikainen.org/hi/brochures/1432.pdf

 

Harold

 

Automan
User Rank
Iron
VERY relevant
Automan   8/5/2011 1:06:53 PM
NO RATINGS
Design News you can use. I have just been diagnosed with Idiopathic Pulmonary Fibrosis. I'm 66 years old and was planning a long retirement after a career as an automotive engineer. Now the prognosis is 3 to 5 years with the possibility of a lung transplant in the future. There is currently no cure.

I will be following this project with great interest.

Dan Barnes 

 

slyoung
User Rank
Iron
Re: VERY relevant
slyoung   8/5/2011 1:31:47 PM
NO RATINGS
You may want look at this video http://youtu.be/lAI5rLnnCBE

 

Page 1/2  >  >>
Partner Zone
More Blogs from Engineering Materials
To give engineers a better idea of the range of resins and polymers available as alternatives to other materials, this Technology Roundup presents several articles on engineering plastics that can do the job.
The first photos made with a 3D-printed telescope are here and they're not as fuzzy as you might expect. A team from the University of Sheffield beat NASA to the goal. The photos of the Moon were made with a reflecting telescope that cost the research team 100 to make (about $161 US).
A tiny humanoid robot has safely piloted a small plane all the way from cold start to takeoff, landing and coming to a full stop on the plane's designated runway. Yes, it happened in a pilot training simulation -- but the research team isn't far away from doing it in the real world.
Some in the US have welcomed 3D printing for boosting local economies and bringing some offshored manufacturing back onshore. Meanwhile, China is wielding its power of numbers, and its very different relationships between government, education, and industry, to kickstart a homegrown industry.
You can find out practically everything you need to know about engineering plastics as alternatives to other materials at the 2014 IAPD Plastics Expo. Admission is free for engineers, designers, specifiers, and OEMs, as well as students and faculty.
Design News Webinar Series
10/7/2014 8:00 a.m. California / 11:00 a.m. New York
9/25/2014 11:00 a.m. California / 2:00 p.m. New York
9/10/2014 11:00 a.m. California / 2:00 p.m. New York
7/23/2014 11:00 a.m. California / 2:00 p.m. New York
Quick Poll
The Continuing Education Center offers engineers an entirely new way to get the education they need to formulate next-generation solutions.
Oct 20 - 24, How to Design & Build an Embedded Web Server: An Embedded TCP/IP Tutorial
SEMESTERS: 1  |  2  |  3  |  4  |  5  |  6


Focus on Fundamentals consists of 45-minute on-line classes that cover a host of technologies. You learn without leaving the comfort of your desk. All classes are taught by subject-matter experts and all are archived. So if you can't attend live, attend at your convenience.
Next Class: 10/28-10/30 11:00 AM
Sponsored by Stratasys
Next Class: 10/28-10/30 2:00 PM
Sponsored by Gates Corporation
Next Class: 11/11-11/13 2:00 PM
Sponsored by Littelfuse
Learn More   |   Login   |   Archived Classes
Twitter Feed
Design News Twitter Feed
Like Us on Facebook

Sponsored Content

Technology Marketplace

Copyright © 2014 UBM Canon, A UBM company, All rights reserved. Privacy Policy | Terms of Service