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Eye-Testing Device May Be Key to Early Alzheimer's Detection

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Jack B
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The earlier the better
Jack B   5/29/2014 10:57:15 AM
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It's nice to see what appears to be a fairly simple test from a patient standpoint, and the ability to begin treating early is essential.

naperlou
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Re: The earlier the better
naperlou   5/29/2014 11:12:33 AM
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You have a good point, Jack.  Early detection at a lower cost point will help us get ahead of this problem.

Charles Murray
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Re: The earlier the better
Charles Murray   6/2/2014 7:51:23 PM
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I agree, naperlou. Earlier detection is the key. It's also going to be important to get insurance companies to understand that.

Daniyal_Ali
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Re: The earlier the better
Daniyal_Ali   5/29/2014 11:57:12 AM
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I agree Jack. Dragging the diagnosis to a point where the drugs and medicine could work effectively should be the ultimate goal when curing any illness. I wonder why the researchers focus more on making strong drugs instead of making a good diagnostic device that could cure the disease using mild drugs.
This device is not only unique but also very helpful as it would allow starting the treatment before the life-threatening symptoms begin.

Elizabeth M
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Re: The earlier the better
Elizabeth M   5/30/2014 6:02:48 AM
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Good point, Daniyal_Ali, about focusing more on a good diagnostic device and less harsh medication. But I have a question--what is the connection between early diagnosis and more mild drugs? Wouldn't the drugs required to cure or stymie the disease be the same no matter when it's detected?

Nancy Golden
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Re: The earlier the better
Nancy Golden   5/30/2014 1:11:10 PM
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Elizabeth, I am guessing what Daniyal_Ali is referring to is that as symptoms progess and worsen, more drastic measures are required. Think of something like cholesterol levels - when caught early - dietary changes, exercise and low doses of a drug (or none at all) will often control it sufficiently. But if a person has had undetected high cholesterol for a longer period of time, plaque may have had a greater chance to develop requiring some sort of medical intervention, and cholesterol levels may have progressed to being much higher than if detected and addressed earlier. This would require higher levels of medication and perhaps different ones since the body has a greater threat to deal with. Or like glaucoma - detecting it early may mean it can be controlled with medicine but if allowed to progress without being diagnosed means that a different approach will be needed involving both medicine and perhaps surgical intervention. I think dosage is a key factor and the risk of side effects always increase as dosage increases. Progressed disease can also call for more powerful drugs which may also have more powerful side effects.

Elizabeth M
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Re: The earlier the better
Elizabeth M   6/3/2014 5:44:51 AM
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Ah, yes, Nancy, thanks for the clarification. I understand what he means now. Perhaps early detection, as you mention, could allow someone to take measures to mitigate the symptoms and causes of the disease and as Daniyal pointed out, allow for less drug intervention later. That's another reason why this test could be such a benefit for people.

Debera Harward
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Re: The earlier the better
Debera Harward   6/13/2014 4:04:38 AM
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Nancy I agree with you any disease when diagnosed at early stage is always favourable not because it will definitely save the life but it helps the patient to remain stable for a longer period of time and helps attendants to be satisfied that they had done what they could do for the health of the patients 

Debera Harward
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Re: The earlier the better
Debera Harward   6/13/2014 4:07:49 AM
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We can also correlate this with Cancer if detected in early stages also there is no surity that the patient will survice but early detection helps more treatement not only more but all the necessary one . So early detection of any disease can is a positive point for taking necessary actions and steps .

Nancy Golden
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Re: The earlier the better
Nancy Golden   5/29/2014 3:52:37 PM
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Being able to replace injecting a patient with a radioactive tracer isotope to do a PET scan with a simple eye ointment and scan sounds like an awesome achievement - and to be able to bring it to the level of family practice even more so. This is a very exciting development.

a.saji
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Re: The earlier the better
a.saji   5/30/2014 1:20:38 AM
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@Nancy: Indeed it is. Any idea of the cost ? 

Elizabeth M
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Re: The earlier the better
Elizabeth M   5/30/2014 5:56:47 AM
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a.saji, not sure of the cost but I can check with the company. I think it may be too early to say since it's not totally in use yet.

Nancy Golden
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Re: The earlier the better
Nancy Golden   5/30/2014 1:13:03 PM
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@a.saji - It looks like a straightforward piece of diagnostic equipment and if it is able to be used in family practice offices, I am betting it will be a lot cheaper than the equipment required for a PET scan. If they can market it to family practices, volume sales will surely help drive the cost down as well - just my opinion.

Elizabeth M
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Re: The earlier the better
Elizabeth M   6/2/2014 3:35:18 AM
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That's an interesting idea, Nancy. I think you're probably right about the volume sales. That seems to be one of the most attractive aspects of this to me--the fact that it can be done in a doctor's office quite easily.

Elizabeth M
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Re: The earlier the better
Elizabeth M   5/30/2014 6:05:08 AM
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Thanks for your comment, Nancy. Yes, it is an awesome achievement. I hope FDA approval comes swiftly to use this machine! What a breakthrough for those dealing with this terrible disease.

Pubudu
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Re: The earlier the better
Pubudu   5/31/2014 10:43:30 PM
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Great innovation in this year, Elizabeth many thanks for sharing those info, will this be lead to have a debilitating free world ?

Elizabeth M
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Re: The earlier the better
Elizabeth M   6/2/2014 3:22:59 AM
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Thanks, Pubudu. I am not sure if this means less people will have Alzheimer's, but at least those who are at risk to develop the disease may have a chance to prepare better for that, and perhaps take advantage of new and experimental drugs.

Elizabeth M
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Re: The earlier the better
Elizabeth M   5/30/2014 5:59:11 AM
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Yes, Jack B, you've hit on the two key points of this invention and why it's so great--early detection and something that is not so invasive for the patient and can be done fairly easily in a doctor's office.

Battar
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Handle it
Battar   6/1/2014 3:24:33 AM
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Software engineers have a saying - "never test for an error condition you don't know how to handle".

Early diagnosis of a medical condition for which there is no known treatment or cure isn't going far to improve anyones' quality of life.  It might actually have a negative efffect on health insurance premiums,

 

Elizabeth M
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Re: Handle it
Elizabeth M   6/2/2014 3:20:16 AM
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That is an interesting perspective, Battar, especially about the insurance prices. But I think that healthcare shouldn't be ruled by something like that and if a person has a chance for early detection and treatment, it still is a good thing. You certainly have good points, though.

William K.
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Re: Handle it
William K.   6/7/2014 8:34:44 PM
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Battar, you are so very wrong about knowing one has a non-treatable problem. That knowledge allows one to abandon the distant future and would certainly change my plans. No need to plan for one's future if one won't be there.

Of course, for those chained by their fears that is a different story. I pity those folks, also those neurotic folks who see everything as a problem that somebody else must fix. One's helping hand is at the end of their arm, so be sure to have the skills that you need, because nobody else will do "it" for you. Whatever "it" happens to be.

Cabe Atwell
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Re: Handle it
Cabe Atwell   6/11/2014 12:35:40 AM
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I agree with you Jack but for the life of me, I can't remember what you wrote. All kidding aside, the thought of catching the disease early would no doubt be incredible, considering it would give us more time to spend with our loved ones. 

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