When Mae West pronounced that too much of a good thing sometimes is a good thing, she probably didn't have the versatile molecule nitric oxide (NO) in mind. However, biologists at Washington University (St. Louis) have shown that a high concentration of NO in osteoclast bone cells might keep them from eating away too much bone, preventing bone loss associated with such diseases as osteoporosis. A team led by Philip Osdoby, a professor of biology, introduced an antibody into the osteoclasts that halted bone resorption, a process where bone is gnawed away by osteoclasts that are too numerous or too active. Biochemical tests showed that, after adding the antibody, an increase in NO occurred, followed by decreases in bone resorption. Osdoby believes that NO acts as a signal to turn the osteoclast off. "With a better understanding of how NO is regulated in osteoclasts, we may be able to develop new strategies to prevent bone loss," Osdoby adds. E-mail Susan_Killenberg@aismail.wustl.edu .
Advertised as the "Most Powerful Tablet Under $100," the Kindle Fire HD 6 was too tempting for the team at iFixit to pass up. Join us to find out if inexpensive means cheap, irreparable, or just down right economical. It's teardown time!
The increased adoption of wireless technology for mission-critical applications has revved up the global market for dynamic electronic general purpose (GP) test equipment. As the link between cloud networks and devices -- smartphones, tablets, and notebooks -- results in more complex devices under test, the demand for radio frequency test equipment is starting to intensify.
Much of the research on lithium-ion batteries is focused on how to make the batteries charge more quickly and last longer than they currently do, work that would significantly improve the experience of mobile device users, as well EV and hybrid car drivers. Researchers in Singapore have come up with what seems like the best solution so far -- a battery that can recharge itself in mere minutes and has a potential lifespan of 20 years.
Some humanoid walking robots are also good at running, balancing, and coordinated movements in group settings. Several of our sports robots have won regional or worldwide acclaim in the RoboCup soccer World Cup, or FIRST Robotics competitions. Others include the world's first hockey-playing robot and a trash-talking Scrabble player.
Focus on Fundamentals consists of 45-minute on-line classes that cover a host of technologies. You learn without leaving the comfort of your desk. All classes are taught by subject-matter experts and all are archived. So if you can't attend live, attend at your convenience.