When Mae West pronounced that too much of a good thing sometimes is a good thing, she probably didn't have the versatile molecule nitric oxide (NO) in mind. However, biologists at Washington University (St. Louis) have shown that a high concentration of NO in osteoclast bone cells might keep them from eating away too much bone, preventing bone loss associated with such diseases as osteoporosis. A team led by Philip Osdoby, a professor of biology, introduced an antibody into the osteoclasts that halted bone resorption, a process where bone is gnawed away by osteoclasts that are too numerous or too active. Biochemical tests showed that, after adding the antibody, an increase in NO occurred, followed by decreases in bone resorption. Osdoby believes that NO acts as a signal to turn the osteoclast off. "With a better understanding of how NO is regulated in osteoclasts, we may be able to develop new strategies to prevent bone loss," Osdoby adds. E-mail Susan_Killenberg@aismail.wustl.edu .
Enabling the Future is designing prosthetic appendages modeled more like superhero arms and hands than your average static artificial limbs. And they’re doing it through a website and grassroots movement inspired by two men’s design and creation in 2012 of a metal prosthetic for a child in South Africa.
In order to keep an enterprise truly safe from hackers, cyber security has to go all the way down to the device level. Icon Labs is making the point that security has to be built into device components.
Three days after NASA's MAVEN probe reached Mars, India's Mangalyaan probe went into orbit around the red planet. India's first interplanetary mission, and the first successful Mars probe launched by an Asian nation, has a total project cost of nearly $600 million less than MAVEN's.
Focus on Fundamentals consists of 45-minute on-line classes that cover a host of technologies. You learn without leaving the comfort of your desk. All classes are taught by subject-matter experts and all are archived. So if you can't attend live, attend at your convenience.