When Mae West pronounced that too much of a good thing sometimes is a good thing, she probably didn't have the versatile molecule nitric oxide (NO) in mind. However, biologists at Washington University (St. Louis) have shown that a high concentration of NO in osteoclast bone cells might keep them from eating away too much bone, preventing bone loss associated with such diseases as osteoporosis. A team led by Philip Osdoby, a professor of biology, introduced an antibody into the osteoclasts that halted bone resorption, a process where bone is gnawed away by osteoclasts that are too numerous or too active. Biochemical tests showed that, after adding the antibody, an increase in NO occurred, followed by decreases in bone resorption. Osdoby believes that NO acts as a signal to turn the osteoclast off. "With a better understanding of how NO is regulated in osteoclasts, we may be able to develop new strategies to prevent bone loss," Osdoby adds. E-mail Susan_Killenberg@aismail.wustl.edu .
With major product releases coming from big names like Sony, Microsoft, and Samsung, and big investments by companies like Facebook, 2015 could be the year that virtual reality (VR) and augmented reality (AR) finally pop. Here's take a look back at some of the technologies that got us here (for better and worse).
Good engineering designs are those that work in the real world; bad designs are those that don’t. If we agree to set our egos aside and let the real world be our guide, we can resolve nearly any disagreement.
The Industrial Internet of Things is bringing a previously reluctant process industry into the wireless fold. The ability to connect smart sensors to the Internet has spiked the demand for wireless devices in process manufacturing, according to the new study from ARC Advisory Group.
Everyone has had the experience of trying to scrape the last of the peanut butter or mayonnaise from the bottom of a glass jar without getting your hand sticky. Inventor Ron Jidmar thinks he has a solution to all of that nonsense with a flexible jar design that can be squeezed with one hand to lift contents from the bottom to the top of a jar or container, leaving the other hand free to scoop the contents out cleanly.
Focus on Fundamentals consists of 45-minute on-line classes that cover a host of technologies. You learn without leaving the comfort of your desk. All classes are taught by subject-matter experts and all are archived. So if you can't attend live, attend at your convenience.