Needles thinner than the diameter of a human hair could form the basis for a new drug-delivery technique able to administer small quantities of high-potency medications through the skin--without causing pain. Arrays of the microneedles could improve administration of existing medications, allow development of new therapeutic compounds, and open the door for microprocessor-based systems for delivering drugs continuously or in response to body needs. In fact, researchers at the Georgia Institute of Technology believe their microneedles would be especially useful with large protein-based molecules, such as those produced through new biotechnology processes. Such drugs often cannot be taken orally, but must be administered frequently enough to make traditional needle injection impractical or unpleasant. Using reactive ion etching microfabrication techniques developed for integrated circuits, Mark G. Allen, associate professor at Georgia Tech's School of Electrical and Computer Engineering, and two graduate students built solid silicon microneedle arrays 10-mm square. Existing needles are 150-mm long and leave holes about one micron in diameter when removed from the skin. Further development, the researchers say, should reduce the length and diameter of their microneedles, make them hollow to increase the rate of drug delivery, and permit mass fabrication of arrays at least a centimeter square. E-mail firstname.lastname@example.org
Samsung's Galaxy line of smartphones used to fare quite well in the repairability department, but last year's flagship S5 model took a tumble, scoring a meh-inducing 5/10. Will the newly redesigned S6 lead us back into star-studded territory, or will we sink further into the depths of a repairability black hole?
In 2003, the world contained just over 500 million Internet-connected devices. By 2010, this figure had risen to 12.5 billion connected objects, almost six devices per individual with access to the Internet. Now, as we move into 2015, the number of connected 'things' is expected to reach 25 billion, ultimately edging toward 50 billion by the end of the decade.
NASA engineer Brian Trease studied abroad in Japan as a high school student and used to fold fast-food wrappers into cranes using origami techniques he learned in library books. Inspired by this, he began to imagine that origami could be applied to building spacecraft components, particularly solar panels that could one day send solar power from space to be used on earth.
Biomedical engineering is one of the fastest growing engineering fields; from medical devices and pharmaceuticals to more cutting-edge areas like tissue, genetic, and neural engineering, US biomedical engineers (BMEs) boast salaries nearly double the annual mean wage and have faster than average job growth.
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